The present report contains an overview of the activities conducted by the United Nations Office on Drugs and Crime in 2019. It also contains a set of recommendations for consideration by the Commission on Narcotic Drugs and the Commission on Crime Prevention and Criminal Justice. The report also contains information submitted pursuant to the requests set out in resolutions 56/9, 62/3, 62/7 of the Commission on Narcotic Drugs and resolution 2019/23 of the Economic and Social Counci.